Prostate-Specific Membrane Antigen (PSMA) (PT1653) mouse mAb

Assay Biotechnology Inc Antibodies and ELISA Kits have been rigorously validated for laboratory grade quality results. High specificity paired with high affinity for targets of interest give researchers an advantage with our products

Catalog No: N1764

Reactivity:Human,Mouse

Applications:IHC-p,IF(paraffin section)

Modification:Unmodfied/ Total

Source:Monoclonal Mouse/IgG1,Kappa

Storage and Stability:-20°C/1 year

Size:

Price/Quantity $190

Quantity:

Datasheet

SDS

Immunohistochemical

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Prostate-Specific Membrane Antigen (PSMA) (PT1653) mouse mAb

Immunohistochemical analysis of paraffin-embedded human prostatic cancer Antibody was diluted at 1:200(4° overnight).

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Antibodies 1-2 business day, ELISA kits 2-3 business day lead time

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Product Details

Product Name

Prostate-Specific Membrane Antigen (PSMA) (PT1653) mouse mAb

Description

folate hydrolase 1(FOLH1)Homo sapiens. This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

Catalog No

N1764

Reactivity

Human, Mouse

Applications

IHC-p,IF(paraffin section)

Modification

Unmodfied/ Total

Source

Monoclonal Mouse/IgG1, Kappa

Dilution

IHC-p 1:100-500，WB 1:500-2000

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

Storage and Stability

-20°C/1 year

Other Name

Molecular Weight (Da)

Gene Name

FOLH1 FOLH NAALAD1 PSM PSMA GIG27

Protein Name

Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)

Human Gene ID

2346

Human Swiss Prot No.

Q04609

Immunogen

Synthesized peptide derived from human Prostate-Specific Membrane Antigen (PSMA)

Specificity

This antibody detects endogenous levels of human Prostate-Specific Membrane Antigen (PSMA). Heat-induced epitope retrieval (HIER) Citrate buffer of pH6.0 was highly recommended as antigen repair method in paraffin section

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.